The African diaspora: history, adaptation and health.

نویسندگان

  • Charles N Rotimi
  • Fasil Tekola-Ayele
  • Jennifer L Baker
  • Daniel Shriner
چکیده

The trans-Atlantic slave trade brought millions of Africans to the New World. Advances in genomics are providing novel insights into the history and health of Africans and the diasporan populations. Recent examples reviewed here include the unraveling of substantial hunter-gatherer and 'Eurasian' admixtures across sub-Saharan Africa, expanding our understanding of ancestral African genetics; the global ubiquity of mixed ancestry; the revealing of African ancestry in Latin Americans that likely derived from the slave trade; and understanding of the ancestral backgrounds of APOL1 and LPL found to influence kidney disease and lipid levels, respectively, providing specific insights into disease etiology and health disparities.

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عنوان ژورنال:
  • Current opinion in genetics & development

دوره 41  شماره 

صفحات  -

تاریخ انتشار 2016